The University of the Republic (Spanish: Universidad de la República, sometimes UdelaR) is a public research university in Montevideo, Uruguay. It is the country's oldest and largest university, as well as one of the largest public universities in South America in terms of enrollment. Established in 1849, it has educated the vast majority of Uruguay's professionals throughout history and has maintained a leading role in advancing academic research and higher education.

The University of the Republic enrolls more than 140,000 students and is organized into 16 independent faculties. It administers 7 university schools and scientific institutes, the Hospital Clinic Manuel Quintela, as well as three regional university centers that serve different parts of the country.