Loyola School is a private college preparatory school on the Upper East Side of the Manhattan borough of New York City, founded in 1900 by the Society of Jesus. It is located two city blocks east of Central Park and Museum Mile on 83rd Street and Park Avenue.

Originally a boys' school, it became co-educational in 1973, becoming the only Jesuit co-educational college preparatory high school in the tri-state area. The school has a student enrollment of two hundred, with an average class size of fifteen students.

The Church of St. Ignatius Loyola is in the same complex and is used for various school functions. The church is listed as a New York City landmark and the complex is listed as a National Historic Place. The Saint Ignatius Loyola School is a grammar school that also shares the complex, but there is no official link between the schools.