The University of St. Michael's College (USMC) is a federated university in the University of Toronto, located on its St. George campus. It was founded in 1852 by the Congregation of St. Basil and retains its Catholic affiliation through its postgraduate theology faculty. Its largest component however is its undergraduate college for liberal arts and sciences, St. Michael's College, one of the seven colleges in the Faculty of Arts and Science.

St. Michael's is most closely associated with teaching and research in the humanities and in theology. It is also known for being home to Marshall McLuhan throughout his influential career as a philosopher and communication theorist, from 1946 until his death in 1980. Both the Pontifical Institute of Mediaeval Studies and Metropolitan Andrey Sheptytsky Institute of Eastern Christian Studies reside within the college. St. Michael's College School is an affiliated boys school which was once the high school section of the college.