York Memorial Collegiate Institute is a public secondary school in Toronto, Ontario, Canada. It is administered by Toronto District School Board (TDSB), de jure located at 2690 Eglinton Avenue West. Prior to 1998, the school was part of the legacy Board of Education for the City of York.

The school opened in 1929 at the Keele and Eglinton area in what was then the Township of York. At 1,350 students, the school is often referred to as "Memo" by its students. Its motto is Macte Nova Virtute (Go forth with new strength).