Lincoln-Sudbury Regional High School (LSRHS or LS) is a public regional high school in Sudbury, Massachusetts, with a 99% graduation rate. The school was founded in 1954, and the building was replaced prior to the 2004–2005 academic year, with additional facilities added in subsequent years.

The school takes residents of Hanscom Air Force Base who are not dependents of active duty military personnel. Dependents of active duty military personnel living on base are instead sent to Bedford High School.