Wolfson College () is a constituent college of the University of Oxford in England. Wolfson is a graduate college, with particular strengths in areas like global health, environmental studies, economics, and humanities. It is located in north Oxford along the River Cherwell. The historian and philosopher Sir Isaiah Berlin was the college's first president and was instrumental in its founding in 1965. The college houses The Isaiah Berlin Literary Trust and hosts an annual Isaiah Berlin Lecture. From 2017, the president of the college has been Sir Tim Hitchens.

As of 2021, the college had a financial endowment of £60.4 million, and is registered as a charity. Wolfson's sister college at the University of Cambridge is Darwin College.