Università Cattolica del Sacro Cuore or Catholic University of the Sacred Heart, colloquially the Catholic University of Milan (Italian: Università Cattolica di Milano) or simply the Cattolica, is an Italian private Catholic research university founded in 1921. Its main campus is located in Milan, Italy, with satellite campuses in Brescia, Piacenza, Cremona and Rome.

The university is organised into 12 faculties and 7 postgraduate schools. Cattolica provides undergraduate courses (bachelor's degree, which corresponds to Italian Laurea Triennale), postgraduate courses (master's degree, which corresponds to Laurea Magistrale, and specializing master) and PhD programs. In addition to these, the university runs several double degree programs with other institutions throughout the world. Degrees are offered both in Italian and in English.

Agostino Gemelli University Hospital serves as the teaching hospital for the medical school of the Università Cattolica del Sacro Cuore and owes its name to the university founder, the Franciscan friar, physician and psychologist Agostino Gemelli.