Champlain College Lennoxville is the Champlain Regional College campus serving the Eastern Townships (Estrie). The campus is located in the borough of Lennoxville, of Sherbrooke, Quebec, Canada. Like the other campuses of Champlain Regional College, the Lennoxville campus is an English-language public post-secondary institution.

Champlain College Lennoxville shares a campus with its neighbour, Bishop's University. In 2024 the college faced several accusations of psychological harassment and creating a toxic workplace from current and former employees.