The High School for Health Professions and Human Services is a public high school in Manhattan, New York City. It is specialized for students preparing for careers in the healthcare and human resources fields.

The curriculum emphasizes the academic preparation necessary for these fields. Students take four years of both mathematics and science, and there are elective research programs and college level courses in both the sciences and the humanities. The High School for Health Professions and Human Services offers a range of science courses as part of a traditional high school curriculum. Top students may conduct research with mentors at nearby hospitals and a few may even compete in the Intel Science Talent Search. The school also offers courses in nutrition, forensics, and a combined art and anatomy class.