The Isenberg School of Management is the business school and also the second largest school at the University of Massachusetts Amherst, the flagship campus for the University of Massachusetts system. The Isenberg School is accredited by the AACSB International and ACPHA.

The school offers seven undergraduate majors along with MS, MBA and Ph.D. programs. As of the 2014-2015 academic year, there were approximately 3500 undergraduate students and 1300 graduate students enrolled in the Isenberg School of Management. As of 2025, Isenberg School has more than 48,000 alumni worldwide across 80 countries.