The School of Advanced International Studies (SAIS) is a graduate school of Johns Hopkins University based in Washington, D.C. The school also maintains campuses in Bologna, Italy and Nanjing, China.

The school is devoted to the study of international relations, diplomacy, national security, economics, and public policy. The school has hosted world leaders on a regular basis for public debate in international affairs.

The school was established in 1943 by Paul Nitze and Christian Herter who were seeking new methods of preparing men and women to cope with the international responsibilities that would be thrust upon the United States in the post-World War II world. Nitze feared the diplomatic and economic expertise developed in World War II might get lost if the nation became isolationist. Originally founded as a standalone graduate school, it became a part of Johns Hopkins University in 1950.

The school's DC campus is located in the 420,000-square-foot 555 Pennsylvania Avenue building, which was purchased by the university in 2019 and has undergone extensive renovation. Previously, the school was based on Embassy Row at Massachusetts Avenue.