Proper name Saint Francis Preparatory School, commonly referred to as St. Francis Preparatory School or St. Francis Prep., is a private, independent Catholic college preparatory school in Fresh Meadows, Queens, New York City, New York. It is the largest non-diocesan Catholic high school in the United States. St. Francis is run by the Franciscan Brothers of Brooklyn, who maintain a residence on the top floor of the school. As of the 2015–16 school year, enrollment at St. Francis was 2,489.