St Cyres School is an 11–18 mixed, English-medium, community secondary school and sixth form in Penarth, Vale of Glamorgan, Wales. It was established in 1958.

Until June 2012, the school was split over two sites: the larger site at Penarth, and a smaller lower school (years 7 to 9) in the nearby village of Dinas Powys. The school has since been unified and moved into a new site, in the Penarth Learning Community.