Hampshire College is a private liberal arts college in Amherst, Massachusetts, United States. It was established in 1965 as an experiment in alternative education, in association with four other colleges in the Pioneer Valley: Amherst College, Smith College, Mount Holyoke College, and the University of Massachusetts Amherst. Together they are known as the Five College Consortium. The campus also houses the National Yiddish Book Center and Eric Carle Museum, and hosts the annual Hampshire College Summer Studies in Mathematics.

The college uses an alternative curriculum, with an emphasis on progressive pedagogy and self-directed academic concentrations, a focus on portfolios rather than distribution requirements, and a reliance on narrative evaluations instead of grades and GPAs.

On April 14, 2026, the college's leaders announced that it would close after the autumn 2026 semester, citing unresolved financial and accreditation pressures.