John Burroughs School (JBS) is a private, non-sectarian college-preparatory school with 631 students in grades 7–12. Its 49-acre (200,000 m²) campus is located in Ladue, Missouri, a suburb of St. Louis. Founded in 1923, it is named for U.S. naturalist and philosopher John Burroughs.

John Burroughs has long had a school philosophy of liberal and progressive education. It has been recognized as one of the nation's premier preparatory schools. In 2007, the Wall Street Journal ranked it among the top 50 schools in sending graduates to eight top universities.

As of 2020, the faculty includes 96 full-time and 32 part-time members. Since 2009, the head of school has been Andy Abbott, formerly an English teacher and the school's head of college counseling. He replaced Keith Shahan, who served as headmaster for 23 years.