Scotch Plains-Fanwood High School (or SPFHS) is a comprehensive regional four-year public high school in Union County, in the U.S. state of New Jersey, which serves students in ninth through twelfth grades from the Township of Scotch Plains and the Borough of Fanwood, operating as the lone secondary school of the Scotch Plains-Fanwood Regional School District. The school is accredited until January 2031 and has been accredited by the Middle States Association of Colleges and Schools Commission on Elementary and Secondary Schools since 1932.

As of the 2023–24 school year, the school had an enrollment of 1,551 students and 115.9 classroom teachers (on an FTE basis), for a student–teacher ratio of 13.4:1. There were 55 students (3.5% of enrollment) eligible for free lunch and 17 (1.1% of students) eligible for reduced-cost lunch.