University of Texas Health Science Center at San Antonio

The University of Texas at San Antonio Health Science Center Campus (UT Health SA or UT San Antonio Health Science Center) is a public academic health science center in San Antonio, Texas and is the medical education, and clinical branch of UT San Antonio.

It is located in the South Texas Medical Center and serves San Antonio and all of the 50,000 square miles (130,000 km²) area of Central and South Texas. It extends to campuses in the Texas border communities of Laredo and the Lower Rio Grande Valley.

The UT San Antonio Health Science Center produces more than 42,550 graduates; more than 4,700 students a year train in an environment that involves more than 100 affiliated hospitals, clinics and health care facilities in South Texas. The university offers more than 65 degrees, the large majority of them being graduate and professional degrees, in the biomedical and health sciences fields.

The Health Science Center Campus is home to the Mays Cancer Center, which is in partnership with the MD Anderson Cancer Center and is a designated a National Cancer Institute Cancer Center. The Mays Cancer Center's Institute for Drug Development (IDD) is internationally recognized for conducting one of the largest oncology Phase I clinical drug trials programs in the world. Fifteen of the cancer drugs most recently approved by the U.S. Food & Drug Administration underwent development or testing at the IDD. Other noted programs include: cellular and structural biology, urology, nephrology, transplantation biology, aging and longevity studies, cardiology and research imaging. UT San Antonio Medical School publishes a periodic magazine, Mission.

In August 2024, the University of Texas Board of Regents announced that the University of Texas at San Antonio and UT Health Science Center at San Antonio would merge to form a "world class university in San Antonio." The integrated universities will retain the UTSA name.

On August 22, 2025 the university was soft launched into the merger as part of the new UT San Antonio branding. The merger officially took effect on September 1, 2025, effectively folding UT Health SA into the new UT San Antonio.