Santa Isabel College Manila

The Santa Isabel College, also referred to by its acronym SIC, is a private, Roman Catholic college owned and operated by the Sisters of Charity of Saint Vincent De Paul in Ermita, Manila, Philippines. It was founded on 24 October 1632. Santa Isabel College is one of the oldest colleges in the Philippines and in Asia.

In 2018, its administration building and the chapel of the Sto. Cristo de Tesoro was declared National Cultural treasure by the National Museum of the Philippines.