Archbishop Quigley Preparatory Seminary was an American seminary preparatory school administered by the Roman Catholic Archdiocese of Chicago for young men considering the priesthood. It closed in 2007, and became the Archbishop Quigley Center in 2008.

The school was named by Cardinal George Mundelein in honor of his predecessor in the area, Archbishop James Edward Quigley.

The school's on-site Chapel of St. James, with stained glass modeled after Sainte-Chapelle in Paris, was dedicated on the 75th anniversary of the Archdiocese of Chicago and the 25th anniversary of Mundelein's priestly ordination on 10 June 1920. It has been listed on the National Register of Historic Places since 1996.

The Quigley seminaries have educated almost 2,500 priests, two cardinals, over forty-one bishops, two Vatican II periti, separate recipients of the Medal of Honor and the Presidential Medal of Freedom, the Order of Merit of the Republic of Poland, and, in sports, two members of the Basketball Hall of Fame.